The Synthesis and Characterization of Copper(ii) Complexes Cont
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چکیده
The synthesis and characterization, spectroscopic, and biological studies of 2-acetylferrocenyl-4phenylthiosemicarbazone, 2-acetylferrocenyl-4-methylthiosemicarbazone, 2-acetylpyridine-2thiophenecarboxylsemicarbazone and 2-acetylferrocenyl-2-thiophenecarboxylsemicarbazone with copper(II) chloride are reported here. The ligands were synthesized by condensation reaction of appropriate carbonyl and amine compounds. The reactions were carried out in the presence of acetic acid. The complexes were characterized by means of Elemental Analysis (EA), Fourier Transform Infrared (FT-IR) spectroscopy, Nuclear Magnetic Resonance (HNMR and CNMR) spectroscopy. The metal complexes and their corresponding ligands were tested against malaria parasites. It was found that the copper complexes synthesized are more biologically active then their corresponding ligands.
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